Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
MVA-EBO Z
- Development stage
- Phase 1
- Lead developer
- University of Oxford
- Modality
- Vaccines & Immunotherapeutics, Viral Vectors → Gene Addition/Replacement → Gene Therapies
- Administration
- Intramuscular
01
Overview
MVA-EBO Z is a recombinant, replication-deficient, attenuated modified vaccinia Ankara (MVA) viral vector vaccine expressing the wild-type glycoprotein (GP) of the Zaire Mayinga strain of Ebola virus. It is designed to induce immune responses against the Ebola virus and has been evaluated both as a standalone immunization and as part of heterologous prime-boost regimens with other Ebola vaccines such as ChAd3-EBO-Z. The vaccine is manufactured using an immortalized duck cell line, which allows for scalable production. Clinical trials have demonstrated that MVA-EBO Z is safe, well-tolerated, and immunogenic in healthy adults in multiple countries. Its primary indication is prophylactic vaccination against infection by the Zaire ebolavirus species[1][3][7].
- Other names
- modified vaccinia Ankara Ebola Zaire vaccinerecombinant modified vaccinia virus Ankara EBOV vaccine
02
Targets
EBOV GP (Zaire ebolavirus glycoprotein GP1,2 and soluble GP)
Beyond the preview
Go deeper on MVA-EBO Z.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on MVA-EBO Z.