Drug intelligence / Profile preview

MVBL

Development stage
Preclinical
Lead developer
Minjiang University
Modality
Small Molecules
Administration
Oral
01

Overview

MVBL is a multi-component combination drug consisting of four compounds: L-selenium-methylselenocysteine (MSC), D-alpha-tocopheryl succinic acid (VES), beta-carotene (beta-Ca), and L-lysine (Lys). Developed as an adjuvant therapy for cancer, it aims to inhibit tumor metastasis, enhance immune function, and provide antioxidant support. The mechanism involves reducing reactive oxygen species (ROS) levels, inhibiting tumor cell migration and invasion, and sensitizing cancer cells to chemotherapy agents like paclitaxel. Preclinical studies in mouse models have demonstrated its ability to prolong survival and reduce lung metastasis.

02

Targets

MMP12 (Macrophage Metalloelastase)HIF1A (Hypoxia-inducible factor 1-alpha)STAT3 (Signal Transducer and Activator of Transcription 3)NF-κB

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