Drug intelligence / Profile preview

MWTx 04

Development stage
Preclinical
Lead developer
Mabwell Therapeutics
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
01

Overview

MWTX-04 is a fully human monoclonal antibody developed by Mabwell Therapeutics that selectively targets Muscle-specific kinase (MuSK). MuSK is a receptor tyrosine kinase critical for the formation and maintenance of the neuromuscular junction (NMJ). By precision-targeting MuSK, MWTX-04 aims to enhance efficacy and reduce off-target effects compared to systemic treatments for muscle diseases. The drug is currently in preclinical development, with lead candidates being evaluated in animal models for indications such as muscle atrophy and dystrophy.

Other names
MWTX-04MWTX04MWTX 04
02

Targets

MUSK (Muscle skeletal receptor tyrosine-protein kinase MuSK)

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