Drug intelligence / Profile preview

MY006

Development stage
Phase 1
Lead developer
Mabylon
Modality
Trispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Subcutaneous
01

Overview

MY006 is a first-in-class, half-life extended trispecific monoclonal antibody developed as a passive immunotherapy for the treatment of peanut allergy. It is designed to provide continuous protection from allergic reactions due to peanut exposure with only a few subcutaneous injections per year. The antibody targets multiple allergenic epitopes on peanut proteins, aiming to neutralize them and prevent IgE-mediated allergic responses. Developed by Mabylon AG, a Swiss biotech company spun out from the University of Zurich and University Hospital Zurich, MY006 leverages naturally occurring human antibodies for its therapeutic effect. The program has received support through collaborations with Pfizer (via Pfizer Ignite) and funding from European research initiatives[2][4][5][6].

02

Targets

Ara h 1 (Peanut allergen Ara h 1)

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