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Mycogone nigra is a non-standardized allergenic extract derived from the fungus *Mycogone nigra*, used for the diagnosis and treatment of mold-related allergies. As a diagnostic tool, it is used in skin testing (percutaneous or intradermal) to identify immediate hypersensitivity (Type I) reactions. As a therapeutic agent, it is used in allergen immunotherapy (subcutaneous injections) to reduce clinical symptoms by inducing immunological tolerance. The extract contains a complex mixture of proteins and polysaccharides from the fungal source. It is manufactured by companies such as Greer Laboratories and is often included in multi-allergen mixes like Rinkel Mold Mix B.
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