Drug intelligence / Profile preview

mycophenolate mofetil (Austrak)

Development stage
Unknown
Lead developer
Austrak
Modality
Small Molecules
Administration
Oral
01

Overview

Immuphen is an immunosuppressant drug developed by Austrak. It is available in formulations containing mycophenolate mofetil (Immuphen 500) or mycophenolate sodium (Immuphen-S 180 and Immuphen-S 360). Mycophenolate is a prodrug of mycophenolic acid, which acts as a potent, selective, and reversible inhibitor of inosine-5'-monophosphate dehydrogenase (IMPDH). By inhibiting IMPDH, mycophenolate blocks the de novo synthesis of guanosine nucleotides, which is essential for the proliferation of T and B lymphocytes. Immuphen is primarily used in nephrology and rheumatology/orthopedics, particularly for the prophylaxis of organ rejection in patients receiving kidney transplants and for the treatment of autoimmune conditions such as lupus nephritis.

Brand names
ImmuphenImmuphen 500Immuphen500Immuphen-500Immuphen-SImmuphen-S 180Immuphen-S180Immuphen-S-180Immuphen-S 360Immuphen-S360Immuphen-S-360
Other names
mycophenolate mofetilmycophenolate sodiummycophenolic acid
02

Targets

IMPDH (Inosine-5'-monophosphate dehydrogenase 1)

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