Drug intelligence / Profile preview

Mycosubtilin

Development stage
Preclinical
Lead developer
Xinjiang Normal University
Modality
Peptides
01

Overview

Mycosubtilin: sourced facts only. name: "SPR analysis supported direct, reversible binding of Myco to immobilized p38α under the tested in vitro conditions." [PMID:42731185]; target: "SPR analysis supported direct, reversible binding of Myco to immobilized p38α under the tested in vitro conditions." [PMID:42731185]; developer: "Xinjiang Key Laboratory of Special Species Conservation and Regulatory Biology, College of Life Science, Xinjiang Normal University, Urumqi, China." [PMID:42731185]; modality: "mycosubtilin (Myco), a Bacillus subtilis-derived cyclic lipopeptide" [PMID:42731185]; stage: "Myco significantly suppressed HepG2 proliferation in a dose- and time-dependent manner and inhibited xenograft tumor growth, with preliminary tolerability indicated by stable body weight and histopathological examination of selected organs." [PMID:42731185]

02

Targets

MAPK14 (p38 mitogen-activated protein kinase alpha)

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