Drug intelligence / Profile preview

Mynalic

Development stage
Unknown
Lead developer
Alborz Zagros
Modality
Small Molecules
Administration
Oral
01

Overview

Mynalic is a generic formulation of mycophenolate sodium (originally marketed under the brand name Myfortic), developed and manufactured by Alborz Zagros. It is an immunosuppressant agent formulated as delayed-release oral tablets (available in 180 mg and 360 mg strengths) designed to prevent organ rejection in patients undergoing kidney transplantation. Mynalic works by reversibly and uncompetitively inhibiting inosine-5'-monophosphate dehydrogenase (IMPDH), specifically targeting both the IMPDH1 and IMPDH2 isoforms. This enzyme is critical for the de novo synthesis of guanosine nucleotides, a pathway upon which T- and B-lymphocytes are highly dependent for proliferation. By blocking this pathway, Mynalic suppresses lymphocyte proliferation and antibody production, thereby preventing the recipient's immune system from rejecting the transplanted kidney.

Brand names
Mynalic
Other names
Mycophenolate SodiumMycophenolic Acid
02

Targets

IMPDH (Inosine-5'-monophosphate dehydrogenase 1)

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