myo-inositol + berberine hcl + alpha lipoic acid + diindolylmethane + d-chiro-inositol

This is a **combination dietary supplement** containing five ingredients: - **myo-inositol**: a carbocyclic sugar that acts as a cellular messenger and plays a key role in insulin signaling and glucose metabolism. - **berberine hcl**: an isoquinoline alkaloid derived from plants (notably Berberis species) with evidence of insulin-sensitizing, hypoglycemic, and metabolic modulation properties. - **alpha lipoic acid**: a cofactor for mitochondrial enzymes with antioxidant activity; enhances insulin sensitivity and supports energy metabolism. - **diindolylmethane**: a compound formed from the digestion of indole-3-carbinol (cruciferous vegetables), modulating estrogen metabolism. - **d-chiro-inositol**: another inositol isomer with effects on insulin signaling, particularly beneficial in insulin resistance and polycystic ovary syndrome (PCOS). The combination is designed to support **metabolic health, insulin sensitivity, hormonal balance, and glucose homeostasis**, especially in metabolic syndrome, PCOS, and insulin resistance. There is evidence for the benefits of smaller subsets (notably myo-inositol plus d-chiro-inositol, with or without alpha lipoic acid; berberine individually) for these indications[1][2][3][4][5]. The use of all five ingredients simultaneously is seen in certain supplement products, but robust clinical data for this exact combination are not published.