Drug intelligence / Profile preview

myo-inositol + D-chiro-inositol + folic acid

Development stage
Preclinical
Lead developer
Lo.Li. Pharma
Modality
Small Molecules
Administration
Oral
01

Overview

myo-inositol + D-chiro-inositol + folic acid is a nutritional supplement combination, notably marketed under the brand name INOFOLIC Combi, designed to address conditions linked to insulin resistance. The formulation typically contains a specific ratio of myo-inositol and D-chiro-inositol, which act as insulin mimetics and secondary messengers in the insulin signaling pathway, alongside folic acid to support metabolic and reproductive health. It is primarily utilized in the management of polycystic ovary syndrome (PCOS) to improve ovulatory function, hormonal balance, and glycemic control, and is also investigated for its benefits in type 2 diabetes, gestational diabetes, and metabolic syndrome.

Brand names
INOFOLIC Combi
Other names
myo-inositol/D-chiro-inositol/folic acidMI/DCI/FA
02

Targets

INSR (Insulin receptor)MTHFR (Methylenetetrahydrofolate reductase)

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