Drug intelligence / Profile preview

Myo-P3

Development stage
Preclinical
Lead developer
Release Therapeutics
Modality
Cell Therapies
Administration
Implant
01

Overview

Myo-P3 is an investigational encapsulated cell therapy developed by Release Therapeutics for the treatment of advanced melanoma. The therapy utilizes the company's proprietary Encapsulation Cell Technology (ECT), which consists of genetically engineered cells housed within a semi-permeable polymer capsule. These cells are designed to continuously produce and secrete an anti-CTLA-4 monoclonal antibody directly into the patient's system. By providing a steady, long-term release of the checkpoint inhibitor, Myo-P3 aims to maintain therapeutic levels of the drug while potentially minimizing the peak-related toxicities and dosing frequency associated with traditional intravenous administrations of CTLA-4 inhibitors like ipilimumab.

Brand names
Myo-P3Myo-P-3Myo-P 3
Other names
Myo-P3Myo-P-3Myo-P 3
02

Targets

CTLA-4 (Cytotoxic t-lymphocyte–associated protein 4)

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