Drug intelligence / Profile preview

Myostatin inhibitory-D-peptide-35

Development stage
Preclinical
Modality
Peptides
Administration
Transdermal, Intramuscular
01

Overview

Myostatin inhibitory-D-peptide-35 (MID-35) is a peptide therapeutic agent under investigation for the treatment of sarcopenia, a public health issue affecting older adults characterized by skeletal muscle loss. The drug functions by inhibiting myostatin, a protein known to limit muscle growth. It is being developed for non-invasive intramuscular delivery via iontophoresis, a transdermal drug delivery technology that uses weak electricity to facilitate the passage of macromolecules from the skin surface to skeletal muscle.

02

Targets

Activin AGDF11 (Growth differentiation factor 11)GDF8 (Myostatin)TGFB1 (Transforming growth factor Beta-1 proprotein)

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