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myristica fragrans essential oil
- Development stage
- Preclinical
- Lead developer
- Mathrusri Ramabai Ambedkar Dental College & Hospital
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Inhalation, Oral, Topical
01
Overview
Myristica fragrans essential oil, commonly known as nutmeg essential oil, is a volatile oil obtained from the seeds or kernels of the *Myristica fragrans* tree. It contains a complex mixture of bioactive compounds, including sabinene, myristicin, alpha-pinene, beta-pinene, and terpinene-4-ol. The essential oil is widely investigated for its diverse pharmacological properties, including antimicrobial, anti-inflammatory, antioxidant, and analgesic activities. In clinical research, it has been evaluated as an alternative obturating material in pediatric pulpectomy (root canal filling of primary teeth) and as an active ingredient in mouthwash formulations for plaque and halitosis control. Additionally, it is being actively researched as a natural biopesticide and botanical insecticide to control *Aedes* mosquito populations and stored-product pests.
- Other names
- MFEOMyristica fragrans oilnutmeg essential oilnutmeg oil
02
Targets
GABAA (Gamma-aminobutyric acid receptor)
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