Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
myristica fragrans seed extract
- Development stage
- Preclinical
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Myristica fragrans seed extract, derived from the nutmeg plant, is a botanical substance investigated for its metabolic and hypoglycemic properties. Its primary bioactive constituent, macelignan, functions as a dual agonist of peroxisome proliferator-activated receptors alpha (PPARα) and gamma (PPARγ). By activating these nuclear receptors, the extract enhances insulin sensitivity and modulates lipid and glucose metabolism. Preclinical research in Swiss albino mice suggests that the extract can significantly reduce blood glucose levels, particularly when co-administered with sulfonylureas like glimepiride, indicating potential utility in the management of type 2 diabetes and metabolic syndrome.
- Other names
- nutmeg extractMyristica fragrans extract
02
Targets
PPARG (Peroxisome proliferator-activated receptor gamma)PPARA (Peroxisome proliferator-activated receptor alpha)
Beyond the preview
Go deeper on myristica fragrans seed extract.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on myristica fragrans seed extract.