Drug intelligence / Profile preview

MYRRHINIL-INTEST (Repha)

Development stage
Unknown
Lead developer
Repha
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

MYRRHINIL-INTEST is a herbal medicinal product developed by REPHA GmbH Biologische Arzneimittel, primarily indicated for the treatment of gastrointestinal disorders such as non-specific diarrhea, flatulence, and cramping. The formulation is a combination of three active botanical components: myrrh (Commiphora myrrha), coffee charcoal (Coffea arabica), and chamomile flower dry extract (Matricaria chamomilla). Myrrh acts as an anti-inflammatory and astringent agent; coffee charcoal serves as an adsorbent for toxins and metabolic products while also providing astringent properties; and chamomile extract offers spasmolytic and anti-inflammatory effects. In Germany, it is also utilized as a maintenance therapy for inflammatory bowel diseases, specifically ulcerative colitis, to prolong remission periods. It is currently being investigated in a Phase IV clinical trial for its efficacy and safety in patients with diarrhoea-predominant irritable bowel syndrome (IBS-D).

Brand names
MYRRHINIL-INTEST
Other names
Myrrh + coffee charcoal + chamomile extract
02

Targets

IL-6 (Interleukin 6)IL10 (Interleukin-10)

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