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myrtol
- Development stage
- Unknown
- Lead developer
- Pohl-Boskamp
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Myrtol is a standardized phytotherapeutic distillate derived from the essential oils of eucalyptus (Eucalyptus globulus), sweet orange (Citrus aurantifolia or Citrus sinensis), lemon (Citrus limon), and myrtle (Myrtus communis) in a fixed ratio of 66:32:1:1. The main active monoterpenes are (+)-α-pinene, d-limonene, and eucalyptol. Myrtol exhibits mucosecretolytic (mucus-dissolving) properties and has additional antioxidant, anti-inflammatory, antibacterial, and bronchospasmolytic effects. Its mechanism includes inhibition of leukocyte activation during inflammation—reducing oxidative cell damage—and inhibition of 5-lipoxygenase activity in basophils/eosinophils to decrease leukotriene production. Clinically it is used for acute and chronic bronchitis as well as sinusitis to facilitate mucus clearance from the respiratory tract[2][5][6].
- Brand names
- MyrtolGeloMyrtolGeloMyrtol forteGeloDurat
- Other names
- ELOM-080ELOM080ELOM 080standardized myrtol
02
Targets
ALOX12 (Arachidonate 12-lipoxygenase, 12S type)SMPD1 (Acid sphingomyelinase)LTC4S (Leukotriene C4 synthase)
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