N,N-dimethyl(5-(pyridin-3-yl)furan-2-yl)methanamine

N,N-dimethyl(5-(pyridin‑3‑yl)furan‑2‑yl)methanamine is a synthetic small molecule belonging to the aralkylamines chemical class. It is an experimental compound that has not been approved for any therapeutic use. The molecule was developed as part of research into selective inhibitors of human cytochrome P450 2A6 (CYP2A6), an enzyme involved in nicotine metabolism and drug biotransformation. Structural studies show that this compound acts as a reversible inhibitor by coordinating to the heme iron of CYP2A6, with its pyridyl moiety forming hydrogen bonds within the active site, leading to high selectivity for CYP2A6 over other P450 isoforms[4]. No clinical trials or approved indications are reported for this agent[1][2][4].

Other names

dimethyl({[5-(pyridin-3-yl)furan-2-yl]methyl})aminedimethyl(((5-(pyridin-3-yl)furan-2-yl)methyl))amineN,N-dimethyl(5-(pyridin‑3‑yl)furan‑2‑yl)methanamine