Drug intelligence / Profile preview

N-(1-carboxy-3-phenylpropyl)phenylalanyl-alpha-asparagine

Development stage
Unknown
Modality
Peptides, Small Molecules
01

Overview

N-(1-carboxy–3–phenylpropyl)phenylalanyl-alpha-asparagine is a synthetic tripeptide small molecule, classified as an experimental compound. It has been studied primarily as a peptide-based inhibitor of elastase, particularly the elastase enzyme from Pseudomonas aeruginosa. Elastase is a proteolytic enzyme involved in tissue degradation and bacterial virulence; thus, inhibitors like this compound are of interest for potential anti-infective or anti-inflammatory applications. There are no approved indications or marketed products containing this molecule[2][3][4].

Other names
N-(1-carboxy-3-phenylpropyl)phenylalanyl-asparagineN-(1-CARBOXY-3-PHENYLPROPYL)PHENYLALANYL-alpha-ASPARAGINE(2S)-2-{[(1S)-1-carbamoyl‑2‑carboxyethyl]carbamoyl}-2‑phenylethyl]amino}-4‑phenylbutanoic acidN-[ (1S)-1-carboxy‑3‑phenylpropyl ] -L‑phenylalanyl-L-alpha-asparagine
02

Targets

LasB (Pseudomonas aeruginosa elastase)

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