n-(2,3,4,5,6-pentafluorobenzyl)-4-sulfamoyl-benzamide

N-(2,3,4,5,6-Pentafluorobenzyl)-4-sulfamoyl-benzamide is a synthetic small molecule belonging to the class of n-benzylbenzamides. It features a benzamide core substituted with a pentafluorobenzyl group and a sulfamoyl moiety. This compound is primarily studied as an experimental inhibitor of carbonic anhydrase 2 (CA II), an enzyme involved in pH regulation and fluid balance in tissues. The compound exhibits high affinity for CA II (reported Kd ~2 nM), suggesting potential utility as a research tool or lead structure for developing carbonic anhydrase inhibitors. There are no approved therapeutic indications or clinical trials reported for this molecule[1][2][3].

Other names

N-(2,3,4,5,6-pentafluoro-benzyl)-4-sulfamoyl-benzamideN-[(2,3,4,5,6-pentafluorophenyl)methyl]-4-sulfamoylbenzamide