N-(2-thienylmethyl)-2,5-thiophenedisulfonamide

N-(2-thienylmethyl)-2,5-thiophenedisulfonamide is a synthetic small molecule featuring a thiophene ring substituted with sulfonamide groups at the 2 and 5 positions and an N-linked thienylmethyl group. It has been studied primarily as a potent inhibitor of carbonic anhydrase enzymes, particularly carbonic anhydrase II. The compound exhibits high binding affinity (Kd ~0.83 nM) for this target[4]. Its structure makes it of interest in medicinal chemistry for the development of enzyme inhibitors and potential pharmaceutical agents targeting diseases where carbonic anhydrase activity is implicated[4][7]. There are no known approved clinical uses or marketed products containing this compound.

Other names

N2-(thiophen-2-ylmethyl)thiophene-2,5-disulfonamide2-N-(thiophen-2-ylmethyl)thiophene-2,5-disulfonamide