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N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide
- Development stage
- Preclinical
- Modality
- Small Molecules
01
Overview
N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide is an experimental small molecule compound belonging to the naphthalene class, characterized by a naphthalene moiety fused with a pyrazole ring and cyclopropane group. It has been studied primarily as an inhibitor of cyclin-dependent kinase 2 (CDK2), targeting the CDK2/cyclin-A complex, which plays a key role in cell cycle regulation. The compound has demonstrated potential anti-tumor and anti-inflammatory activities in preclinical research settings[1][3][8]. Its mechanism involves binding to and inhibiting CDK2 activity, thereby interfering with cell proliferation pathways relevant to cancer biology[6][8].
- Other names
- N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(naphthalen-2-yl)acetamideN-(5-cyclopropyl-1H-pyrazol-3-yl)-2-(2-naphthyl)acetamide326823-27-2
02
Targets
CCNA2 (Cyclin A2)CDK2 (Cyclin-dependent kinase 2)
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