Drug intelligence / Profile preview

N-(4-carbamimidoyl-3-chlorophenyl)-2-hydroxy-3-iodo-5-methylbenzamide

Development stage
Unknown
Modality
Small Molecules
01

Overview

N-(4-carbamimidoyl-3-chlorophenyl)-2-hydroxy-3-iodo-5-methylbenzamide is a synthetic small molecule belonging to the benzanilide class, characterized by its complex aromatic structure with halogen (chlorine and iodine) and amidine functional groups. It has been studied primarily as a research compound in medicinal chemistry for its potential to modulate or inhibit serine proteases involved in coagulation and fibrinolysis pathways, such as coagulation factor X, plasminogen, prothrombin, tissue-type plasminogen activator (tPA), trypsin, and urokinase-type plasminogen activator. Its mechanism of action is presumed to involve direct inhibition of these serine proteases through binding at their active sites. The compound’s unique structure makes it valuable for probing enzyme function and developing new anticoagulant or thrombolytic agents[6][4].

Other names
n-(4-carbamimidoyl-3-choro-phenyl)-2-hydroxy-3-iodo-5-methyl-benzamideN-(4-carbamimidoyl-3-chlorophenyl)-2-hydroxy-3-iodo-5-methylbenzamide
02

Targets

PLG (Plasminogen)F10 (Factor Xa)PLAU (uPA)PLAT (Tissue-type plasminogen activator)F2 (Thrombin)

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