N-(biphenyl-4-ylsulfonyl)-D-leucine

N-(biphenyl-4-ylsulfonyl)-D-leucine is a synthetic small molecule and a derivative of the amino acid leucine, featuring a biphenyl ring system connected to a sulfonamide group. It acts as an inhibitor of macrophage metalloelastase, an enzyme involved in tissue remodeling and inflammation. This compound has been studied primarily as an experimental tool or discovery agent in medicinal chemistry and biochemistry for its potential to modulate inflammatory pathways and tissue repair mechanisms. There are no approved indications or clinical trials beyond preclinical research[1][7][9].

Other names

(2R)-4-methyl-2-(4-phenylbenzenesulfonamido)pentanoic acid(R)-2-(biphenyl-4-ylsulfonamido)-4-methylpentanoic acidN-(4-biphenylylsulfonyl)-D-leucine(2R)-4-methyl-2-[ (4‑phenylphenyl)sulfonylamino ]pentanoic acid