Drug intelligence / Profile preview

N-2-thiophen-2-yl-acetamide boronic acid

Development stage
Unknown
Modality
Small Molecules
01

Overview

N-2-thiophen-2-yl-acetamide boronic acid is a small molecule experimental compound belonging to the class of heteroaromatic organic compounds. It features a thiophene ring and a boronic acid moiety, which are known for their ability to interact with biological targets through reversible covalent bonding. This compound has been investigated primarily as an inhibitor of beta-lactamase enzymes, which are responsible for antibiotic resistance in bacteria. Boronic acids like this one have shown potential anti-inflammatory, antimicrobial, and antiviral activities due to their unique chemical reactivity[1][3]. However, there are no approved indications or clinical trials reported for this specific molecule[2].

Other names
((2-(thiophen-2-yl)acetamido)methyl)boronic acid{[(2-thienylacetyl)amino]methyl}boronic acid[2-(thiophen-2-yl)acetamido]methylboronic acidBoronic acid, B-[[(2-(2-thienyl)acetyl]amino]methyl]
02

Targets

AmpC (AmpC beta-lactamase)

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