N-acetyl cysteine + alpha lipoic acid + liposomal glutathione (Merz)

N-acetyl cysteine (NAC), alpha lipoic acid (ALA), and liposomal glutathione represent a combination of potent antioxidant compounds intended to enhance cellular defense against oxidative stress and inflammation. N-acetyl cysteine serves as a precursor for the synthesis of glutathione, the body's primary endogenous antioxidant. Alpha lipoic acid is a versatile dithiol compound that can scavenge free radicals and regenerate other antioxidants like vitamins C and E. Liposomal glutathione provides a direct, encapsulated form of the tripeptide to improve systemic bioavailability. This combination has been explored for its potential to mitigate oxidative stress-induced damage in dermatological conditions such as atopic dermatitis. However, it is important to note that the specific Phase 3 clinical trial context often associated with Merz North America in atopic dermatitis (MSRD-100) specifically evaluates desoximetasone, a topical corticosteroid, rather than this antioxidant mixture, suggesting a discrepancy between the drug name and the clinical trial context provided.

Brand names

Auro GSH

Other names

NAC + ALA + GlutathioneAntioxidant Protocol