Drug intelligence / Profile preview

N-acetylcysteine + calcitriol + hydroxychloroquine

Development stage
Unknown
Lead developer
Galectin Therapeutics
Modality
Small Molecules
Administration
Oral, Intravenous, Inhalation
01

Overview

This is a combination of three distinct medications:\n\n1. N-acetylcysteine (NAC): An antioxidant medication primarily used as an antidote for acetaminophen overdose. It works by replenishing glutathione levels, the body's major antioxidant. NAC also has mucolytic properties, breaking up mucus in the lungs and airways.\n\n2. Calcitriol: The active form of vitamin D that helps regulate calcium and phosphorus metabolism.\n\n3. Hydroxychloroquine: An antimalarial and disease-modifying anti-rheumatic drug (DMARD) used to treat autoimmune conditions like lupus and rheumatoid arthritis. It's thought to work by interfering with immune system communication.\n\nThis specific combination does not appear to be a standard formulation with established clinical use.

02

Targets

GSH (Glutathione synthesis / redox)VDR (Vitamin D receptor)

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