Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
n-acetyltryptophan
- Development stage
- Preclinical
- Modality
- Small Molecules
- Administration
- Intrathecal
01
Overview
N-acetyltryptophan is a naturally occurring small molecule derivative of the amino acid tryptophan. It functions as an inhibitor of the neurokinin 1 receptor (NK1R), the primary receptor for the neuropeptide substance P. Research has explored its potential neuroprotective effects, particularly in models of Parkinson's disease, where it appears to reduce neuroinflammation and preserve blood-brain barrier integrity. Historically, salts of N-acetyltryptophan were investigated for treating psychiatric disorders such as depression and manic-depressive psychoses. Currently, it is widely used as a research reagent, a pharmaceutical excipient, and an impurity reference standard (Tryptophan Related Compound B).
- Other names
- N-acetyl-L-tryptophanTryptophan Related Compound BNAT
02
Targets
TACR1 (Neurokinin‑1 Receptor)TIL (Tryptophan indole-lyase)
Beyond the preview
Go deeper on n-acetyltryptophan.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on n-acetyltryptophan.