Drug intelligence / Profile preview

N-ethylretinamide

Development stage
Preclinical
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
01

Overview

N-Ethylretinamide is a synthetic derivative of all-trans-retinoic acid (vitamin A acid), specifically the ethylamide of all-trans β-retinoic acid. It has a molecular formula of C22H33NO and a molecular weight of approximately 327.5 g/mol. The compound is structurally related to retinoids, which are known for their roles in cell differentiation, proliferation, and apoptosis through modulation of nuclear retinoic acid receptors (RARs). While detailed pharmacological data or clinical use information for N-Ethylretinamide itself is limited in the available sources, its structure suggests it may act as a modulator of retinoid signaling pathways[8][10]. No approved therapeutic indications or marketed products containing this compound were identified.

Other names
all-trans-N-ethylretinamideRetinamide, N-ethyl-Retinoic acid ethyl amideVitamin A acid ethylamiden-ethyl retinamide
02

Targets

RARA (Retinoic acid receptor alpha)RARG (Retinoic acid receptor gamma)RARB (Retinoic acid receptor beta)

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