Drug intelligence / Profile preview

n-isopropyl butylone

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

N-Isopropyl butylone is a novel synthetic stimulant and substituted cathinone, structurally related to other beta-keto methylenedioxyamphetamines (noted by the "-ylone" suffix). Its formal chemical name is 1-(1,3-benzodioxol-5-yl)-2-(isopropylamino)butan-1-one. The compound was first identified in August 2024. It appears as an off-white crystalline material and has a molecular formula of C14H19NO3 with a molecular weight of 249.3 g/mol. While its precise pharmacological activity and potency are currently unknown, it is expected—based on structural similarity to other substituted cathinones—to act as a central nervous system stimulant with potential for psychoactive effects similar to amphetamines[1][7]. Like related compounds, it may function as a monoamine transporter inhibitor or releaser (serotonin, norepinephrine, dopamine), though this has not been directly confirmed for N-isopropyl butylone.

Other names
3,4-methylenedioxy-α-isopropylaminobutiophenoneisopropylbutylone
02

Targets

SERT (Sodium-dependent serotonin transporter)DAT (Dopamine plasma membrane transport protein)NET (Norepinephrine Transporter)

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