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N-nonyldeoxynojirimycin (NN-DNJ) is a synthetic small molecule and a derivative of deoxynojirimycin in which the amino hydrogen is replaced by a nonyl group. It acts as an inhibitor of glucosidase enzymes, specifically targeting acid α-glucosidase and α-1,6-glucosidase. By inhibiting these enzymes, NN-DNJ disrupts carbohydrate metabolism pathways and leads to increased glycogen levels in hepatic and muscle tissues. The compound demonstrates high intestinal absorption but limited blood-brain barrier penetration. It is not significantly metabolized by cytochrome P450 enzymes[2][6].
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