Drug intelligence / Profile preview

n-pyridoxyl-glycine-5-monophosphate

Development stage
Unknown
Modality
Small Molecules
01

Overview

N-Pyridoxyl-Glycine‑5‑Monophosphate is a synthetic small molecule derivative of pyridoxamine (a form of vitamin B6), in which glycine is conjugated to the pyridoxal ring and a phosphate group is attached at the 5-position. It acts as an experimental inhibitor of ornithine decarboxylase, an enzyme involved in polyamine biosynthesis. The compound has been studied primarily as a biochemical tool and not as an approved pharmaceutical agent. There are no known clinical indications or marketed formulations for this molecule[1][2][5].

Other names
N-PYRIDOXYL-GLYCINE-5-MONOPHOSPHATEN-PYRIDOXYL-GLYCINE5-MONOPHOSPHATEN-PYRIDOXYL-GLYCINE 5-MONOPHOSPHATE2-[({3-hydroxy-2-methyl-5-(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]acetic acidN-glycine-[3-hydroxy-2-methyl–5-phosphonoozymethyl-pyridin–4–yl-methane]N-(3-hydroxy–2-methyl–5-(phosphonooxy)methyl)pyridin–4–yl)methyl)glycine
02

Targets

ODC1 (Ornithine decarboxylase)

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