Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
N1-dansylspermine
- Development stage
- Unknown
- Modality
- Small Molecules
- Administration
- Not Applicable (research Compound; Typically Used In Vitro Or Ex Vivo Experimental Settings)
01
Overview
N1-dansylspermine is a synthetic small molecule consisting of a spermine backbone conjugated at the N1 position with a dansyl (5-dimethylaminonaphthalene-1-sulfonyl) group. It is primarily used as a biochemical probe and is known to act as an antagonist of the N-methyl-D-aspartate (NMDA) receptor, a subtype of glutamate receptor in the central nervous system. Through antagonism of NMDA receptors, it can modulate synaptic transmission and is commonly used in research to study ion channel block and polyamine modulation mechanisms. The compound itself is not marketed as a therapeutic pharmaceutical, but is widely used in neuropharmacology research as a reference or tool compound[1][4][5].
- Brand names
- NMDA Antagonist XI
- Other names
- dansyl spermineN1-dansyl-spermineN-1-dansyl-spermineN 1-dansyl-spermineN1-dansyl-spermidineN-1-dansyl-spermidineN 1-dansyl-spermidine
02
Targets
NMDAR (Glutamate receptor ionotropic, NMDA)
Beyond the preview
Go deeper on N1-dansylspermine.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on N1-dansylspermine.