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n3-(3-pyridin-3-ylbenzyl)pyridine-2,3-diamine

Development stage: Unknown
Modality: Small Molecules

Overview

N3-(3-pyridin-3-ylbenzyl)pyridine-2,3-diamine, also known by code names 2ohr, 8IP, and CHEMBL220346, is a synthetic small molecule. It functions as a potent inhibitor of p21-activated kinases (PAK) 1, 2, and 3. Due to its role as a PAK inhibitor, it is primarily used as a research tool in studies exploring the role of PAK enzymes in various cellular processes, including cell growth, survival, and cytoskeletal dynamics. It has been characterized crystallographically when bound to PAK1.

Other names: N~3~-(3-Pyridin-3-Ylbenzyl)pyridine-2,3-DiamineN~3~-[3-(Pyridin-3-yl)phenyl]methylpyridine-2,3-diamineN~1~-[{[(Pyridin-2-yl)amino]methyl}phenyl]-N1-pyridinamine2ohr8IP

Targets

PAK3 (P21 (RAC1) activated kinase 3)PAK2PAK1 (p21-activated kinase 1)

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