Drug intelligence / Profile preview

N76-1

Development stage
Preclinical
Lead developer
Chongqing Medical University
01

Overview

N76-1: sourced facts only. name: "Kinase activity and cellular thermal shift assays showed that N76-1 directly targeted CDK7." [PMID:37429520]; target: "Kinase activity and cellular thermal shift assays showed that N76-1 directly targeted CDK7." [PMID:37429520]; developer: "Department of Pharmacology, College of Pharmacy, Chongqing Medical University, Chongqing, 400016, China; Chongqing Key Laboratory of Drug Metabolism, Chongqing, 400016, China; Key Laboratory for Biochemistry and Molecular Pharmacology of Chongqing, Chongqing, 400016, China." [PMID:37429520]; stage: "Moreover, N76-1 markedly inhibited the growth of TNBC xenografts and phosphorylation of RNAPII in tumor tissues." [PMID:37429520]

02

Targets

CDK7

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