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NAI006

Development stage: Preclinical
Lead developer: Hangzhou Nain Biotechnology
Modality: PROTACs (E3 ligase recruitment) → Targeted Protein Degraders (TPDs) → Small Molecules, Bivalent/Multivalent Binders → Multivalent & Scaffold-Based Small Molecules → Small Molecules

Overview

NAI006 is a preclinical-stage proteolysis-targeting chimera (PROTAC) being developed by Hangzhou Nain Biotechnology for the treatment of solid tumors. As a PROTAC, the molecule is designed to recruit an E3 ubiquitin ligase to a specific target protein, leading to the protein's ubiquitination and subsequent degradation by the proteasome. While the specific biological target of NAI006 has not yet been disclosed by the developer, the program is part of Hangzhou Nain's pipeline focused on targeted protein degradation for oncology.

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