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NAL1215 (ketoprofen)
- Development stage
- Preclinical
- Lead developer
- Nal Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Transdermal
01
Overview
NAL1215 is a transdermal patch formulation of the nonsteroidal anti-inflammatory drug (NSAID) ketoprofen, currently under development by NAL Pharmaceutical Group. Designed for once-daily application, the patch utilizes a transdermal delivery system to provide sustained release of ketoprofen for the management of pain. Ketoprofen exerts its therapeutic effect by inhibiting the enzymes cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2), which are critical for the biosynthesis of prostaglandins involved in pain and inflammatory responses. This delivery modality is intended to offer a convenient alternative to oral NSAIDs, potentially reducing gastrointestinal side effects and improving patient adherence.
- Other names
- Ketoprofen 1-Day PatchKetoprofen1-Day PatchKetoprofen-1-Day Patch
02
Targets
PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)
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