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NAL1242
- Development stage
- Preclinical
- Lead developer
- Nal Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Transdermal
01
Overview
NAL1242 is a transdermal patch formulation of glycol salicylate currently under development by NAL Pharmaceutical Group for pain management. Designed as a 12-hour extended-release over-the-counter (OTC) product, NAL1242 utilizes a specialized delivery system to provide sustained relief from musculoskeletal pain and inflammation. The active ingredient, glycol salicylate, is a topical nonsteroidal anti-inflammatory drug (NSAID) that exerts its effects by inhibiting the cyclooxygenase enzymes COX-1 and COX-2, thereby reducing the production of pro-inflammatory prostaglandins at the site of application. The program is currently in the preclinical stage of development.
- Other names
- Glycol Salicylate 12-Hour Patchglycol salicylate2-hydroxyethyl salicylate
02
Targets
PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)
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