Drug intelligence / Profile preview

NAL6329

Development stage
Preclinical
Lead developer
Nal Pharmaceuticals
Modality
Small Molecules
Administration
Transdermal
01

Overview

NAL6329 is a transdermal patch formulation of formoterol, a long-acting beta-2 adrenergic receptor agonist (LABA), developed by NAL Pharmaceutical Group. The product is designed as a once-daily (1-day) patch for the treatment of respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). By utilizing a transdermal delivery system, NAL6329 aims to provide sustained and stable systemic levels of formoterol, potentially offering improved patient compliance and a more consistent therapeutic effect compared to traditional inhaled bronchodilators. The mechanism of action involves the activation of beta-2 adrenergic receptors on airway smooth muscle cells, leading to muscle relaxation and increased airflow. It is currently in the preclinical stage of development.

Other names
Formoterol 1-Day PatchFormoterol1-Day PatchFormoterol-1-Day PatchFormoterol transdermal patch
02

Targets

ADRB2 (β2)

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