Drug intelligence / Profile preview

NAL8812

Development stage
Preclinical
Lead developer
Nal Pharmaceuticals
Modality
Small Molecules
Administration
Transdermal
01

Overview

NAL8812 is a transdermal patch formulation of donepezil, an acetylcholinesterase inhibitor, being developed by NAL Pharmaceutical Group for the treatment of Alzheimer's disease. The patch is designed for 3-day (twice-weekly) administration, utilizing NAL's proprietary transdermal delivery technology to provide sustained release of the drug. By inhibiting acetylcholinesterase, it increases the concentration of acetylcholine in the brain, which is intended to improve cognitive function in patients with Alzheimer's. The transdermal route aims to reduce gastrointestinal side effects and improve patient compliance compared to oral formulations.

Other names
Donepezil 3-Day PatchDonepezil3-Day PatchDonepezil-3-Day Patch
02

Targets

Acetylcholinesterase

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