nalbuphine + Long dan xie gan tang

nalbuphine + Long dan xie gan tang is a drug-herb combination investigated for potential pharmacokinetic and pharmacodynamic interactions. Nalbuphine is a semi-synthetic opioid analgesic that functions as a kappa-opioid receptor agonist and a mu-opioid receptor antagonist. Long dan xie gan tang (LDXGT), also known as Gentiana Decoction to Drain the Liver, is a traditional Chinese herbal formula typically used to treat conditions associated with damp-heat in the liver and gallbladder. The Tri-Service General Hospital conducted Phase 1 clinical research to evaluate how the co-administration of LDXGT affects the safety, metabolism, and efficacy of nalbuphine in healthy subjects. This study specifically aimed to identify herb-drug interactions that might alter the clinical profile of the opioid analgesic when used alongside traditional herbal medicine.

Brand names

Nubian

Other names

Nalbuphine with Long dan xie gan tangNubian with Long dan xie gan tangnalbuphine + Long dan xie gan tang-Tri-Service General Hospital