Nalpha-(2-Naphthylsulfonylglycyl)-3-Amidino-D,L-Phenylalanine-Isopropylester

Nalpha-(2-Naphthylsulfonylglycyl)-3-Amidino-D,L-Phenylalanine-Isopropylester is a synthetic small molecule belonging to the class of serine protease inhibitors. It is structurally characterized as a peptide derivative and has been studied primarily as an experimental compound, not approved for clinical use. The compound acts by binding to the active site of serine proteases such as trypsin and thrombin, inhibiting their enzymatic activity. Structural studies have shown that it fits into the specificity pocket of these enzymes, with its amidinophenylalanine moiety engaging key residues in the active site[1][4][5]. Its primary research application has been in structural biology and enzymology for understanding protease-inhibitor interactions.

Other names

methyl (2S)-3-(3-carbamimidoylphenyl)-2-[2-(4-methylbenzenesulfonamido)acetamido]propanoateCAS 133397-81-6CAS133397-81-6CAS-133397-81-6DB01737DB-01737DB 01737