Drug intelligence / Profile preview

naltrexone + nicotine

Development stage
Unknown
Modality
Small Molecules
Administration
Oral, Transdermal
01

Overview

Naltrexone + nicotine is a combination therapy used for smoking cessation. Naltrexone is an opiate blocker that works by inhibiting the chemical signals within the brain that convey pleasure when people use drugs such as nicotine. When combined with nicotine replacement therapy (typically delivered via patches), this combination helps reduce cigarette cravings and lessens withdrawal discomfort. Research has shown this combination to be particularly effective for women, boosting smoking cessation rates by almost 50 percent when assessed after eight weeks of treatment. The combination also helps prevent the weight gain commonly associated with smoking cessation.

02

Targets

DOR (Opioid Receptor Delta 1)MOR (Mu opioid receptor)α4β2 nAChR (Nicotinic acetylcholine receptor alpha4 beta2 subtype)KOR (Kappa opioid receptor)CHRNA7 (α7 nicotinic receptor)

Beyond the preview

Go deeper on naltrexone + nicotine.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on naltrexone + nicotine.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call