Drug intelligence / Profile preview

Naltrexone POA Pharma

Development stage
Unknown
Lead developer
POA Pharma
Modality
Small Molecules
Administration
Oral
01

Overview

Naltrexone POA Pharma is a generic formulation of naltrexone hydrochloride, a potent and long-acting opioid antagonist. Commercialized by Galen (a member of the Almac Group) following its acquisition of POA Pharma, the drug is used as an adjunct in the treatment of alcohol and opioid dependence. It functions by competitively binding to opioid receptors in the central nervous system, effectively blocking the euphoric effects of exogenous opioids and reducing the craving for alcohol. The product is typically administered orally as a 50 mg film-coated tablet and is intended for use in patients who have already undergone detoxification and are committed to maintaining abstinence.

Brand names
Naltrexone POA Pharma
Other names
naltrexone hydrochloride
02

Targets

DOR (Opioid Receptor Delta 1)KOR (Kappa opioid receptor)MOR (Mu opioid receptor)

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