NAMPT gene therapy

NAMPT gene therapy is a regenerative medical intervention developed by Integrated Health Systems (IHS) designed to address age-related metabolic decline and associated conditions. The therapy involves the delivery of genetic material to upregulate the expression of nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme in the NAD+ salvage pathway. By increasing NAMPT levels, the treatment aims to enhance the biosynthesis of nicotinamide adenine dinucleotide (NAD+), a crucial coenzyme that declines with age and is essential for mitochondrial function, DNA repair, and cellular energy homeostasis. This therapy is offered as part of a concierge medical service focused on longevity and regenerative medicine, rather than through traditional pharmaceutical development channels.

Other names

NAMPT upregulationnicotinamide phosphoribosyltransferase upregulation