Nanjing Univ. of Chinese Medicine CSF-1R compound III-1

Nanjing Univ. of Chinese Medicine CSF-1R compound III-1: sourced facts only. name: "Among these derivatives, compound III-1 was strongly bound to CSF-1R and showed potent CSF-1R inhibitory activity." [PMID:40013758]; target: "Among these derivatives, compound III-1 was strongly bound to CSF-1R and showed potent CSF-1R inhibitory activity." [PMID:40013758]; developer: "Jiangsu Key Laboratory for Functional Substance of Chinese Medicine, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, P. R. China." [PMID:40013758]; stage: "More importantly, III-1 showed demonstrated efficacy against patient-derived colorectal cancer organoids and exhibited stronger anticolorectal cancer efficacy in vivo compared to PLX3397, highlighting its potential in the immunotherapy of colorectal cancer." [PMID:40013758]