Drug intelligence / Profile preview

Nanjing Univ. of Chinese Medicine NLRP3 compound D6

Development stage
Preclinical
Lead developer
Nanjing University of Chinese Medicine
01

Overview

Nanjing Univ. of Chinese Medicine NLRP3 compound D6: sourced facts only. name: "Thus, D6 is proved as a potent NLRP3 inhibitor, and has the potential to develop as a novel anti-ALI agent." [PMID:39197252]; target: "Thus, D6 is proved as a potent NLRP3 inhibitor, and has the potential to develop as a novel anti-ALI agent." [PMID:39197252]; developer: "Jiangsu Key Laboratory for Functional Substance of Chinese Medicine, School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China." [PMID:39197252]; stage: "Finally, D6 demonstrated a favorable therapeutic effect on LPS-induced ALI in mice model, and the potent pharmacodynamic effect of D6 was correlated with the specific inhibition of NLRP3 inflammasome activation in vivo." [PMID:39197252]

02

Targets

NLRP3 (Nod-like receptor family pyrin domain-containing protein 3)

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