Drug intelligence / Profile preview

nano carbonate apatite

Development stage
Unknown
Lead developer
Second Affiliated Hospital of Zhejiang University School of Medicine
Modality
Nanoparticles → Drug Delivery Systems
Administration
Topical
01

Overview

Nano carbonate apatite (n-CAP) is a synthetic biomaterial, a modified form of hydroxyapatite, which constitutes the primary inorganic component of dentine and bone. Its crystalline structure incorporates carbonate ions, differentiating it from pure hydroxyapatite. The 'nano' designation refers to its nanometer-scale particle size, which imparts enhanced surface energy, biocompatibility, and superior adhesion to dental surfaces. In dental applications, n-CAP is employed in toothpastes to alleviate dentine hypersensitivity by physically occluding exposed dentinal tubules and actively promoting the remineralization of compromised dentine and enamel.

02

Targets

Hydroxyapatite

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