Drug intelligence / Profile preview

nano selenium

Development stage
Unknown
Lead developer
Dermatology Hospital of Southern Medical University
Modality
Nanoparticles → Drug Delivery Systems
Administration
Oral
01

Overview

Nano selenium (selenium nanoparticles) is a zero-valent form of selenium with particle sizes typically ranging from 5 to 200 nm. Compared to traditional inorganic (selenite, selenate) and organic (selenomethionine) selenium forms, nano selenium exhibits lower toxicity and higher biological activity. It acts primarily as a potent antioxidant and immunomodulator by serving as a critical cofactor for selenoproteins, including glutathione peroxidase (GPx) and thioredoxin reductase (TrxR), which protect cells from oxidative damage. In the context of condyloma acuminatum, oral nano selenium is being investigated as an adjuvant therapy to CO2 laser treatment to enhance the host's antiviral immune response against Human Papillomavirus (HPV) and reduce the risk of lesion recurrence.

Other names
selenium nanoparticlesSeNPsnanoselenium
02

Targets

GPX (Glutathione peroxidase 6)TXNRD2 (Thioredoxin reductase 2)

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