Drug intelligence / Profile preview

nano silver fluoride + tricalcium phosphate

Development stage: Unknown
Lead developer: Tanta University
Modality: Nanoparticles → Drug Delivery Systems, Small Molecules
Administration: Topical

Overview

Nano silver fluoride + tricalcium phosphate is an investigational combination of dental topical agents used for the prevention and inhibition of dental caries. Nano silver fluoride (NSF) acts as an antimicrobial and remineralizing agent; silver nanoparticles provide antibacterial activity against cariogenic bacteria like *Streptococcus mutans*, while fluoride ions promote the formation of fluorapatite, which is more resistant to acid than hydroxyapatite. Tricalcium phosphate (TCP) is a remineralizing agent that releases calcium and phosphate ions to strengthen tooth enamel. This combination is typically applied as a dental varnish, particularly in high-risk populations such as children with special healthcare needs.

Other names: nano silver fluoride + tri calcium phosphateNSF + TCP varnish

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