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NanoDoce (NanOlogy)
- Development stage
- Unknown
- Lead developer
- NanOlogy
- Modality
- Small Molecules, Nanoparticles → Drug Delivery Systems
- Administration
- Intratumoral
01
Overview
NanoDoce is a proprietary, submicron particle formulation of docetaxel developed by NanOlogy, LLC. It utilizes the company's Large Surface Area Microparticle (LSAM) technology to create pure drug particles without the need for surfactants or polymers. This formulation is specifically designed for intratumoral injection, which allows for the sustained release of high concentrations of docetaxel directly into the tumor microenvironment while maintaining low systemic exposure and minimizing toxicity. In the context of renal cell carcinoma, NanoDoce is being evaluated as a local treatment for localized T1a tumors, potentially offering a minimally invasive alternative to surgery or thermal ablation.
- Brand names
- NanoDoce
- Other names
- Nanoparticulate docetaxelLSAM-docetaxelSubmicron docetaxel
02
Targets
TUBB (Tubulin (alpha and beta subunits))
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